• Coffee • Wine • Art

    Chemistry & Community

  • Beer and Cocktails

    Happy Hour M-F 5 - 7

  • Local Art and Events at The Molecule Effect

    Local Art & Events


Located in Denver’s Art District on Santa Fe, The Molecule Effect offers an entirely a new approach to how coffee and wine are represented. Integrating both a wine bar and coffeehouse enhances the unique experience one would have when visiting.

We are locally owned and operated and we like to do things a bit different. To us it’s about the mixture of hand selected items based on quality, integrity and all around deliciousness. We blend this with a great staff and the right amount of things we love like art, and our local culture. Add to this our desire of building community and in that great chemistry is created - that’s “The Molecule Effect.”
The Molecule Effect Employees
Visit The Molecule Effect


Come enjoy a well prepared espresso, our fresh local foods and desserts or the ever so frequent glass of wine, beer or custom cocktail.

Hours: Monday - Friday 6am - 9pm
    Saturday - 7am - 9pm
             Sunday - 7am - 7pm

Address: 1201 Santa Fe Dr, Suite A, Denver, CO 80204
Phone: (720) 502-6966  
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